Subcutaneous injection of water-soluble multi-walled carbon nanotubes in tumor-bearing mice boosts the host immune activity.
Nanotechnology
; 21(14): 145104, 2010 Apr 09.
Article
em En
| MEDLINE
| ID: mdl-20234075
ABSTRACT
The immunological responses induced by oxidized water-soluble multi-walled carbon nanotubes on a hepatocarcinoma tumor-bearing mice model via a local administration of subcutaneous injection were investigated. Experimental results show that the subcutaneously injected carbon nanotubes induced significant activation of the complement system, promoted inflammatory cytokines' production and stimulated macrophages' phagocytosis and activation. All of these responses increased the general activity of the host immune system and inhibited the progression of tumor growth.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Água
/
Nanotubos de Carbono
/
Imunidade
/
Neoplasias
Limite:
Animals
Idioma:
En
Revista:
Nanotechnology
Ano de publicação:
2010
Tipo de documento:
Article