First manifestation of lambda positive plasmacytoma in the orbital apex with acute unilateral loss of vision.
Minim Invasive Neurosurg
; 53(2): 74-6, 2010 Apr.
Article
em En
| MEDLINE
| ID: mdl-20533138
ABSTRACT
INTRODUCTION:
An intracranial plasmacytoma is a rare form, which can involve the calvarium, dura or the cranial base. Only few case reports describe the manifestation of plasmacytoma of the skull base with affection of visual acuity. CASE REPORT We describe the case of a 43-year-old woman, presenting with an acute unilateral loss of vision. The presumption diagnosis was retrobulbar neuritis as first manifestation of multiple sclerosis. MR imaging disclosed a tumour in the left orbital region and a meningioma was suspected. After complete resection with decompression of the optic nerve, the neuropathological examination revealed a lambda positive plasmacytoma. Additional work-up disclosed an involvement of multiple vertebral bodies. Due to the diagnosis of multiple myeloma, oncological therapy had been initiated.CONCLUSION:
Skull base plasmacytoma is a rare disease. Solitary lesions causing neurological deficits should be treated aggressively including surgery for histological diagnosis and decompression of neural structures. Prognosis and further therapy depends on the systemic stage of disease, which has to be defined by diagnostic work-up.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Orbitárias
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Cegueira
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Neoplasias da Base do Crânio
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Mieloma Múltiplo
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
Minim Invasive Neurosurg
Assunto da revista:
NEUROCIRURGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Alemanha