Hematopoietic stem cell transplantation in patients infected with HIV.
Curr HIV/AIDS Rep
; 7(3): 175-84, 2010 Aug.
Article
em En
| MEDLINE
| ID: mdl-20549392
ABSTRACT
Hematopoietic stem cell transplantation (HSCT) replaces a diseased hematopoietic system with a functional, disease-free graft and is frequently used in the treatment of hematologic malignancies. The advent of highly active antiretroviral therapy made it possible to treat medical conditions in HIV-infected patients in the same way as in the general population. Several studies have reported the feasibility, safety, and efficacy of autologous HSCT as rescue or consolidation treatment for non-Hodgkin's and Hodgkin's lymphoma in HIV-infected patients. As a result of the improvements in supportive care and the introduction of attenuated transplant conditioning regimens, allogeneic HSCT has been used to treat life-threatening hematologic disorders, with promising results in HIV-infected patients. Moreover, this strategy has made it possible to treat both the hematologic disease and HIV infection.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Linfoma Relacionado a AIDS
/
Transplante de Células-Tronco Hematopoéticas
/
Terapia Antirretroviral de Alta Atividade
Limite:
Humans
Idioma:
En
Revista:
AIDS Rep
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Espanha