Automated segmentation of myocardial scar in late enhancement MRI using combined intensity and spatial information.
Magn Reson Med
; 64(2): 586-94, 2010 Aug.
Article
em En
| MEDLINE
| ID: mdl-20665801
ABSTRACT
Accurate assessment of the size and distribution of a myocardial infarction (MI) from late gadolinium enhancement (LGE) MRI is of significant prognostic value for postinfarction patients. In this paper, an automatic MI identification method combining both intensity and spatial information is presented in a clear framework of (i) initialization, (ii) false acceptance removal, and (iii) false rejection removal. The method was validated on LGE MR images of 20 chronic postinfarction patients, using manually traced MI contours from two independent observers as reference. Good agreement was observed between automatic and manual MI identification. Validation results showed that the average Dice indices, which describe the percentage of overlap between two regions, were 0.83 +/- 0.07 and 0.79 +/- 0.08 between the automatic identification and the manual tracing from observer 1 and observer 2, and the errors in estimated infarct percentage were 0.0 +/- 1.9% and 3.8 +/- 4.7% compared with observer 1 and observer 2. The difference between the automatic method and manual tracing is in the order of interobserver variation. In conclusion, the developed automatic method is accurate and robust in MI delineation, providing an objective tool for quantitative assessment of MI in LGE MR imaging.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reconhecimento Automatizado de Padrão
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Imageamento por Ressonância Magnética
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Interpretação de Imagem Assistida por Computador
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Cicatriz
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Gadolínio DTPA
/
Infarto do Miocárdio
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
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Prognostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Magn Reson Med
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Holanda