Wrapping BCR-ABL: it's in the bag.
Blood
; 116(18): 3382-3, 2010 Nov 04.
Article
em En
| MEDLINE
| ID: mdl-21051563
ABSTRACT
Leukemia, with its origin in a specific genetic abnormality, will only arise if the cell properly folds and processes the oncogenic protein encoded by the mutant gene. In this issue of Blood, Tsukahara and Maru describe a set of proteins that control the processing of the nascent BCR-ABL oncoprotein, providing new avenues for potential therapeutic intervention in chronic myelogenous leukemia (CML).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Blood
Ano de publicação:
2010
Tipo de documento:
Article