Nuclear magnetic resonance spectra and molecular structure of mesna.
Arzneimittelforschung
; 40(5): 599-602, 1990 May.
Article
em En
| MEDLINE
| ID: mdl-2116804
ABSTRACT
Mesna (2-mercapto-ethane sulfonic acid sodium salt) is used as a reliably acting uroprotector in cancer chemotherapy with oxazaphosphorine cytostatics. 1H-, 13C[1H]- and C,H-COSY-NMR-spectra are analyzed. In solution state mesna exists predominantly in a trans-rotameric form. These findings are supported by hypothetical gas-phase-structures of mesna, simulated via the program system MOPAC.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mesna
/
Mercaptoetanol
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Arzneimittelforschung
Ano de publicação:
1990
Tipo de documento:
Article