Antigen engineering in DNA immunization.
Methods Mol Med
; 29: 355-74, 2000.
Article
em En
| MEDLINE
| ID: mdl-21374335
ABSTRACT
J. A. Wolff and colleagues demonstrated in 1990 (1) that naked, non-infectious DNA plasmids can be transferred into muscle cells of living mice to express the encoded protein in vivo. Further studies have shown that proteins expressed in vivo via such a "DNA inoculation" process can serve as immunogens to effectively stimulate the body's immune system to produce potentially strong, long-lasting, antigen-specific, humoral and cell-mediated immune responses (2-8).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Methods Mol Med
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Marrocos