Inhibition of the cooperative adhesion of Streptococcus sanguis to hydroxylapatite.
FEMS Microbiol Lett
; 59(3): 315-8, 1990 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-2177022
ABSTRACT
The adhesion of Streptococcus sanguis to hydroxylapatite is a process involving several adhesins and receptors. Binding isotherms and Scatchard plots of the adhesion suggest that cooperative interactions occur at low cell densities. It was found that sulfolane, a hydrophobic-bond diluent, was capable of inhibiting the cooperative adhesion of S. sanguis to saliva-coated hydroxylapatite beads. Sodium thiocyanate, a chaotropic agent, inhibited not only cooperative adhesion, but also the adhesion thought to result from noncooperative interactions. It is suggested that strong chaotropic agents may not only inhibit adhesin-receptor complexes, but also may influence the secondary/tertiary structures of interacting species.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Streptococcus sanguis
/
Aderência Bacteriana
/
Hidroxiapatitas
Idioma:
En
Revista:
FEMS Microbiol Lett
Ano de publicação:
1990
Tipo de documento:
Article