Once-weekly fluconazole to prevent recurrence of oropharyngeal candidiasis in patients with AIDS and AIDS-related complex: a double-blind placebo-controlled study.
J Infect
; 21(1): 55-60, 1990 Jul.
Article
em En
| MEDLINE
| ID: mdl-2200826
ABSTRACT
Fluconazole 50 mg daily for 14-28 days was effective in the treatment of patients with AIDS and AIDS-related complex with severe oropharyngeal and oesophageal candidiasis. Of 24 patients entered, 17 (81%), including seven with oesophageal candidiasis, were clinically cured and two (9.5%) improved at the end of treatment. Following clinical cure, 14 patients were entered into the double-blind phase of the study, where fluconazole (150 mg) or placebo capsules were given once weekly. Treatment was double blind. Fluconazole 150 mg once weekly was found to be effective in maintaining patients both clinically and mycologically free of oropharyngeal candidiasis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Candidíase Bucal
/
Doenças Faríngeas
/
Fluconazol
/
Complexo Relacionado com a AIDS
/
Síndrome da Imunodeficiência Adquirida
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Infect
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Reino Unido