Molecular and cytogenetic studies in a case of XX SRY-negative sex reversal in an Arabian horse.
Sex Dev
; 6(1-3): 104-7, 2012.
Article
em En
| MEDLINE
| ID: mdl-22025175
ABSTRACT
An 18-month-old Arabian foal characterized by a stallion-like appearance was submitted for cytogenetic and molecular genetics examinations due to abnormalities of external genitalia and the presence of ovotestis-like structures in the abdominal cavity. By RB-banding the animal showed the normal female equine karyotype (2n = 64,XX). Molecular analysis revealed the absence of the SRY and ZFY genes and the presence of ZFX, a typical female equine condition. The entire RSPO1 coding region was examined to exclude its involvement. Although a SNP was found in exon 3, it was not responsible for an amino acid substitution.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos do Desenvolvimento Sexual
/
Proteína da Região Y Determinante do Sexo
/
Doenças dos Cavalos
Limite:
Animals
Idioma:
En
Revista:
Sex Dev
Assunto da revista:
CIENCIAS DO COMPORTAMENTO
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Itália