Q fever: still more queries than answers.
Adv Exp Med Biol
; 719: 133-43, 2011.
Article
em En
| MEDLINE
| ID: mdl-22125041
ABSTRACT
Q fever is a worldwide zoonosis, caused by C. burnetii. Infection usually occurs through inhalation of infected aerosols. The reservoir mainly consists of dairy cattle. Clinical symptoms of acute Q fever are non-specific and resemble a mild flu-like illness. Children often present with gastrointestinal symptoms and rash. Rarely, chronic infection develops. This is usually manifested as endo-carditis, vascular infection and, in children, osteomyelitis. Diagnosis is based on serology and nucleic acid amplification (PCR). Doxycycline is the treatment of choice for acute infection. An alternative for young children and pregnant women is cotrimoxazole. Chronic infection requires long term treatment usually with doxycycline combined with hydroxychloroquine.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Febre Q
/
Coxiella burnetii
Limite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Adv Exp Med Biol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Holanda