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Equilibrium radionuclide angiography for evaluating the effect of facilitated percutaneous coronary intervention on ventricular synchrony in patients with acute myocardial infarction.
Liu, Jun; Fu, Xiang-Hua; Xue, Ling; Wu, Wei-Li; Gu, Xin-Shun; Li, Shi-Qiang.
Afiliação
  • Liu J; Department of Cardiology, The 1st Hospital of Hebei Medical University, Shijiazhuang 050031, China. liujun32962003@yahoo.com.cn
Circ J ; 76(4): 928-35, 2012.
Article em En | MEDLINE | ID: mdl-22313803
ABSTRACT

BACKGROUND:

It is unclear whether facilitated percutaneous coronary intervention (PCI) via a transradial approach therapy is preferable to primary PCI, with improved ventricular synchrony performance (VS), in Chinese patients. METHODS AND

RESULTS:

The 152 patients with their first anterior acute myocardial infarction (AMI) were randomized to a primary PCI group or facilitated PCI group. In the 1(st) week and 6(th) month after AMI onset, the parameters of VS were measured by equilibrium radionuclide angiography with ventricular phase analysis. The rate of TIMI grade-3 flow in the infarct-related artery pre-PCI in the facilitated PCI group was higher than that in the primary PCI group (30.56% vs. 8.45%, P=0.001). At the 6(th) month post-AMI, the parameters of time to peak ejection rate, phase shift and peak phase standard deviation were lower than in the primary PCI group (P<0.05, respectively). The incidence of recurrent ischemia and new or worsening congestive heart failure post-AMI in the facilitated PCI group was significantly lower than that in the primary PCI group (2.78% vs. 9.86%, P=0.043; 2.78% vs. 12.68%, P=0.028).

CONCLUSIONS:

Facilitated PCI via a transradial approach might significantly inhibit left ventricular remodeling and improve left ventricular function because of the complete, persistent patency of the infarct-related artery with few complications of vessel access and bleeding.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angioplastia Coronária com Balão / Imagem do Acúmulo Cardíaco de Comporta / Função Ventricular Esquerda / Disfunção Ventricular Esquerda / Infarto Miocárdico de Parede Anterior Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Circ J Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2012 Tipo de documento: Article País de afiliação: China
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angioplastia Coronária com Balão / Imagem do Acúmulo Cardíaco de Comporta / Função Ventricular Esquerda / Disfunção Ventricular Esquerda / Infarto Miocárdico de Parede Anterior Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Circ J Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2012 Tipo de documento: Article País de afiliação: China