Late recovery with cyclosporine-A of an auto-immune sudden sensorineural hearing loss.
Acta Otorhinolaryngol Ital
; 31(6): 399-401, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-22323852
ABSTRACT
Sensorineural hearing loss of immune-mediated origin may be present as a symptom in systemic autoimmune diseases or may occur as a primary disorder without other organ involvement (auto-immune inner ear disease). The diagnosis of auto-immune inner ear disease is still predicated on clinical features and to date specific diagnostic tests are not available. We report a case of right-sided sudden hearing loss in a female patient in which the clinical manifestations, in addition to ANA positivity and hypocomplementaemia allowed us to hypothesize an auto-immune inner ear disease. The immunosuppressive treatment with cyclosporine-A was capable of a recovery of the hearing that, however, occurred progressively with normalization of the hearing function after 1 year of treatment. cyclosporine-A could be proposed as a therapeutic option in case of auto-immune inner ear disease allowing the suspension of corticosteroids that, at high dose, expose patients to potentially serious adverse events.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Ciclosporina
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Perda Auditiva Súbita
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Perda Auditiva Neurossensorial
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Imunossupressores
Limite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Acta Otorhinolaryngol Ital
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Itália