[Miller-Dieker syndrome (type I lissencephaly) with specific EEG changes]. / Miller-Dieker-Syndrom (Lissenzephalie Typ I) mit spezifischen EEG-Veränderungen.

ABSTRACT

We present the case report of a girl with a subtype of Lissencephaly syndrome, type I, "Miller-Dieker syndrome", pointing out the specific EEG features in infancy and early childhood. The following pathognomonic EEG manifestations may confirm the diagnosis of an lissencephalic syndrome abnormally fast background activity of an extraordinary high voltage increasing with age, missing topographic structuring, no reactivity to sleep or medication, unusually high-voltaged sharp-slow-wave complexes.