Oropheayunnol, an unusual 22,23-epoxy apotirucallane triterpenoid from Orophea yunnanensis.
Nat Prod Commun
; 7(4): 495-6, 2012 Apr.
Article
em En
| MEDLINE
| ID: mdl-22574451
ABSTRACT
A new apotirucallane-type triterpenoid with an unusual 22,23-epoxy group in the side chain, 22,23-epoxy-apotirucalla-14-ene-3alpha,7alpha,24alpha,25-tetraol (1), was isolated from the leaves and twigs of Orophea yunnanensis. The structure of 1 was established on the basis of HRESIMS, 1D, and 2D NMR spectroscopic methods. This is the first phytochemical study of Orophea yunnanensis, and the biogenetic origin of 1 was postulated. Compound 1 exhibited weak cytotoxicity in vitro against the growth of CNE1 nasopharyngeal carcinoma cell line with an IC50 value of 9.7 microg/mL.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Annonaceae
Idioma:
En
Revista:
Nat Prod Commun
Assunto da revista:
BOTANICA
/
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2012
Tipo de documento:
Article