Induction of apoptosis in MCF-7 cells by ß-1,3-xylooligosaccharides prepared from Caulerpa lentillifera.
Biosci Biotechnol Biochem
; 76(5): 1032-4, 2012.
Article
em En
| MEDLINE
| ID: mdl-22738982
ABSTRACT
ß-1,3-Xylan was prepared from the green alga, Caulerpa lentillifera, and hydrolyzed to oligosaccharides by a mild acid treatment. The average degree of polymerization was about 5. The oligosaccharides reduced the number of viable human breast cancer MCF-7 cells in a dose-dependent manner, and induced chromatin condensation and degradation of poly ADP-ribose polymerase, indicating that they induced apoptosis in MCF-7 cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligossacarídeos
/
Xilanos
/
Extratos Vegetais
/
Apoptose
/
Caulerpa
/
Antineoplásicos Fitogênicos
Limite:
Female
/
Humans
Idioma:
En
Revista:
Biosci Biotechnol Biochem
Assunto da revista:
BIOQUIMICA
/
BIOTECNOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Japão