Cochleovestibular nerve involvement in multifocal fibrosclerosis.
J Laryngol Otol
; 126(9): 935-8, 2012 Sep.
Article
em En
| MEDLINE
| ID: mdl-22874454
ABSTRACT
OBJECTIVES:
To report a case of multifocal fibrosclerosis with a nine-year follow up, and to discuss this disease's radiological appearance and management. The disease is a rare systemic disorder of unknown cause characterised by fibrous proliferation involving multiple anatomical sites. CASE REPORT A 50-year-old woman presented with histological findings characterised by similar inflammatory processes involving the meninges, pituitary gland, peritoneum, retroperitoneum and orbits, prompting a search for a common pathophysiology. A diagnosis of multifocal fibrosclerosis was postulated. Symptom improvement was noted after treatment with prednisone and azathioprine.CONCLUSION:
This is the first documented case of involvement of the cochleovestibular nerve in a patient with multifocal fibrosclerosis. The rare association between fibrotic diseases and masses showing various clinical patterns should be kept in mind by otolaryngologists, and imaging performed to investigate for multifocal fibrosclerosis. However, diagnosis can only be confirmed with tissue biopsy and histopathological examination.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrose Retroperitoneal
/
Doenças do Nervo Vestibulococlear
/
Transtornos de Sensação
/
Meningite
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
J Laryngol Otol
Assunto da revista:
OTORRINOLARINGOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Brasil