Fully automated deformable registration of breast DCE-MRI and PET/CT.
Phys Med Biol
; 58(4): 1221-33, 2013 Feb 21.
Article
em En
| MEDLINE
| ID: mdl-23369926
ABSTRACT
Accurate characterization of breast tumors is important for the appropriate selection of therapy and monitoring of the response. For this purpose breast imaging and tissue biopsy are important aspects. In this study, a fully automated method for deformable registration of DCE-MRI and PET/CT of the breast is presented. The registration is performed using the CT component of the PET/CT and the pre-contrast T1-weighted non-fat suppressed MRI. Comparable patient setup protocols were used during the MRI and PET examinations in order to avoid having to make assumptions of biomedical properties of the breast during and after the application of chemotherapy. The registration uses a multi-resolution approach to speed up the process and to minimize the probability of converging to local minima. The validation was performed on 140 breasts (70 patients). From a total number of registration cases, 94.2% of the breasts were aligned within 4.0 mm accuracy (1 PET voxel). Fused information may be beneficial to obtain representative biopsy samples, which in turn will benefit the treatment of the patient.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Processamento de Imagem Assistida por Computador
/
Mama
/
Neoplasias da Mama
/
Imageamento por Ressonância Magnética
/
Tomografia Computadorizada por Raios X
/
Técnica de Subtração
/
Tomografia por Emissão de Pósitrons
/
Imagem Multimodal
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Revista:
Phys Med Biol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Holanda