Simultaneous determination of cytosine arabinoside and its metabolite, uracil arabinoside, in human plasma using hydrophilic interaction liquid chromatography with UV detection.
Biomed Chromatogr
; 27(7): 818-20, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23420764
ABSTRACT
A practical high-performance liquid chromatography using a Cosmosil HILIC column and UV detection was developed for determining the concentrations of cytosine arabinoside (Ara-C) and uracil arabinoside (Ara-U), which is a major metabolite of Ara-C, in human plasma. This method was used to determine the plasma concentrations of Ara-C and Ara-U in a patient treated with high-dose Ara-C therapy for end-stage renal failure.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arabinofuranosiluracila
/
Cromatografia Líquida de Alta Pressão
/
Citarabina
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Biomed Chromatogr
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Japão