[Protective effect of cytoflavin and its components in mice with acute alloxan intoxication].
Eksp Klin Farmakol
; 76(4): 26-31, 2013.
Article
em Ru
| MEDLINE
| ID: mdl-23762986
ABSTRACT
We have studied the protective effect of cytoflavin and its components (meglumine sodium succinate, riboflavin, inosine and nicotinamide) in mice with acute alloxan intoxication. It is established that cytoflavin and its components possessing in vitro antioxidant activity (riboflavin, inosine and nicotinamide) significantly decrease the hyperglycemic effect of alloxan. The protective effect of cytoflavin in animals with behavioral disorders caused by acute alloxan intoxication is related to the effect of meglumine sodium succinate and inosine, but does not depend on the influence of these substances on free-radical oxidation processes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Succinatos
/
Niacinamida
/
Diabetes Mellitus Experimental
/
Mononucleotídeo de Flavina
/
Hiperglicemia
/
Inosina Difosfato
Limite:
Animals
Idioma:
Ru
Revista:
Eksp Klin Farmakol
Assunto da revista:
FARMACOLOGIA
Ano de publicação:
2013
Tipo de documento:
Article