Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord contributes to chronic visceral pain in rats.

Luo, Xiao-Qing; Cai, Qin-Yan; Chen, Yu; Guo, Li-Xia; Chen, Ai-Qin; Wu, Zhen-Quan; Lin, Chun

Luo, Xiao-Qing; Cai, Qin-Yan; Chen, Yu; Guo, Li-Xia; Chen, Ai-Qin; Wu, Zhen-Quan; Lin, Chun.

Afiliação

Luo XQ; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China; Department of Physiology and Pathophysiology, Laboratory of Pain Research, Key Laboratory of Brain Aging and Neurodegenerative Diseases, Neuroscience Research Center, Fujian Medical Uni
Cai QY; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China; Department of Physiology and Pathophysiology, Laboratory of Pain Research, Key Laboratory of Brain Aging and Neurodegenerative Diseases, Neuroscience Research Center, Fujian Medical Uni
Chen Y; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China; Department of Physiology and Pathophysiology, Laboratory of Pain Research, Key Laboratory of Brain Aging and Neurodegenerative Diseases, Neuroscience Research Center, Fujian Medical Uni
Guo LX; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China; Department of Physiology and Pathophysiology, Laboratory of Pain Research, Key Laboratory of Brain Aging and Neurodegenerative Diseases, Neuroscience Research Center, Fujian Medical Uni
Chen AQ; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China; Department of Physiology and Pathophysiology, Laboratory of Pain Research, Key Laboratory of Brain Aging and Neurodegenerative Diseases, Neuroscience Research Center, Fujian Medical Uni
Wu ZQ; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China.
Lin C; School of Foundational Medical sciences, Fujian Medical University, Fuzhou City, Fujian Province 350108, PR China; Department of Physiology and Pathophysiology, Laboratory of Pain Research, Key Laboratory of Brain Aging and Neurodegenerative Diseases, Neuroscience Research Center, Fujian Medical Uni

Brain Res ; 1542: 167-75, 2014 Jan 13.

Article em En | MEDLINE | ID: mdl-24125810

Assuntos

Receptores de N-Metil-D-Aspartato/metabolismo; Medula Espinal/metabolismo; Tirosina/metabolismo; Dor Visceral/patologia; Animais; Animais Recém-Nascidos; Modelos Animais de Doenças; Relação Dose-Resposta a Droga; Eletromiografia; Antagonistas de Aminoácidos Excitatórios/uso terapêutico; Genisteína/farmacologia; Síndrome do Intestino Irritável/complicações; Masculino; Medição da Dor; Fenóis/uso terapêutico; Fosforilação/fisiologia; Piperidinas/uso terapêutico; Inibidores de Proteínas Quinases/farmacologia; Ratos; Ratos Sprague-Dawley; Fatores de Tempo; Dor Visceral/etiologia

Palavras-chave

Chronic visceral pain; Genistein; N-methyl-d-aspartic acid receptor 2B subunit; Ro 25-6981; Spinal cord; Tyrosine kinase

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medula Espinal / Tirosina / Receptores de N-Metil-D-Aspartato / Dor Visceral Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Brain Res Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google