Azathioprine induced serious portal hypertension: a case series of three IBD patients and review of the literature.
Acta Gastroenterol Belg
; 76(3): 342-6, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-24261031
ABSTRACT
We report 3 male IBD patients (2 Crohn's Disease, 1 Ulcerative Colitis) developing thrombocytopenia and splenomegaly on azathioprine treatment. All patients were diagnosed with significant portal hypertension due to histological proven nodular regenerative hyperplasia (NRH) of the liver. In two of three patients, liver function tests remained completely normal. In addition we provide a short literature review of azathioprine induced NRH covering etiology, imaging, pathology, prognosis and treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Azatioprina
/
Doenças Inflamatórias Intestinais
/
Hipertensão Portal
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Acta Gastroenterol Belg
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Bélgica