Homocysteine in dogs with systemic inflammatory response syndrome.
J Small Anim Pract
; 54(12): 620-4, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24283416
ABSTRACT
OBJECTIVES:
To compare serum concentrations of homocysteine in healthy dogs and those fitting the criteria for systemic inflammatory response syndrome and to compare these values to commonly measured B-vitamins.METHODS:
Study dogs were classified into non-infectious systemic inflammatory response syndrome or sepsis groups and blood was drawn on Day 1 of the patient's hospitalisation for measurement of serum homocysteine, folate and cobalamin concentrations. Homocysteine concentration was measured in 51 clinically healthy dogs to serve as the control group.RESULTS:
A statistically significant difference was found between the homocysteine concentrations of the healthy group when compared to non-infectious systemic inflammatory response syndrome and sepsis groups. Homocysteine values were not correlated with folate, cobalamin or APPLEfast severity scores. Homocysteine concentrations were significantly lower in sick dogs when compared to the control group, which is dissimilar to the human population. CLINICALSIGNIFICANCE:
The clinical significance of homocysteine changes in critically ill dogs is currently unknown.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Resposta Inflamatória Sistêmica
/
Doenças do Cão
/
Homocisteína
Tipo de estudo:
Observational_studies
Limite:
Animals
Idioma:
En
Revista:
J Small Anim Pract
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos