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Synthesis, biological evaluation and SAR of 3-benzoates of ingenol for treatment of actinic keratosis and non-melanoma skin cancer.
Grue-Sørensen, Gunnar; Liang, Xifu; Månsson, Kristoffer; Vedsø, Per; Dahl Sørensen, Morten; Soor, Anke; Stahlhut, Martin; Bertelsen, Malene; Engell, Karen Margrethe; Högberg, Thomas.
Afiliação
  • Grue-Sørensen G; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark.
  • Liang X; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark.
  • Månsson K; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark.
  • Vedsø P; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark.
  • Dahl Sørensen M; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark.
  • Soor A; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark.
  • Stahlhut M; Biological Research, LEO Pharma A/S, 55 Industriparken, DK-2750 Ballerup, Denmark.
  • Bertelsen M; Biological Research, LEO Pharma A/S, 55 Industriparken, DK-2750 Ballerup, Denmark.
  • Engell KM; Product Reprofiling, LEO Pharma A/S, 55 Industriparken, DK-2750 Ballerup, Denmark.
  • Högberg T; Chemical Research, LEO Pharma A/S, 55 Industripaken, DK-2750 Ballerup, Denmark. Electronic address: thomas.hogberg@leo-pharma.com.
Bioorg Med Chem Lett ; 24(1): 54-60, 2014 Jan 01.
Article em En | MEDLINE | ID: mdl-24332494
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Benzoatos / Inibidores de Proteínas Quinases / Diterpenos / Ceratose Actínica / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Benzoatos / Inibidores de Proteínas Quinases / Diterpenos / Ceratose Actínica / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Dinamarca