HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete.

Salman-Dilgimen, Aydan; Hardy, Pierre-Olivier; Radolf, Justin D; Caimano, Melissa J; Chaconas, George

Salman-Dilgimen, Aydan; Hardy, Pierre-Olivier; Radolf, Justin D; Caimano, Melissa J; Chaconas, George.

Afiliação

Salman-Dilgimen A; Department of Biochemistry & Molecular Biology and Department of Microbiology, Immunology & Infectious Diseases, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.
Hardy PO; Department of Biochemistry & Molecular Biology and Department of Microbiology, Immunology & Infectious Diseases, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.
Radolf JD; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, United States of America ; Department of Pediatrics, University of Connecticut Health Center, Farmington, Connecticut, United States of America ; Department of Molecular Microbial and Structural Biology, Univer
Caimano MJ; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, United States of America ; Department of Pediatrics, University of Connecticut Health Center, Farmington, Connecticut, United States of America ; Department of Molecular Microbial and Structural Biology, Univer
Chaconas G; Department of Biochemistry & Molecular Biology and Department of Microbiology, Immunology & Infectious Diseases, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.

PLoS Pathog ; 9(12): e1003841, 2013.

Article em En | MEDLINE | ID: mdl-24367266

Assuntos

Borrelia burgdorferi/genética; Borrelia burgdorferi/patogenicidade; Ixodes/microbiologia; Doença de Lyme/microbiologia; Doença de Lyme/transmissão; RNA Helicases/fisiologia; Processamento Pós-Transcricional do RNA/genética; Animais; Proteínas de Bactérias/fisiologia; Células Cultivadas; Perfilação da Expressão Gênica; Regulação Bacteriana da Expressão Gênica; Doença de Lyme/genética; Masculino; Camundongos; Camundongos Endogâmicos C3H; Organismos Geneticamente Modificados; Virulência/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Lyme / Processamento Pós-Transcricional do RNA / Ixodes / RNA Helicases / Borrelia burgdorferi Limite: Animals Idioma: En Revista: PLoS Pathog Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Canadá

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