Acute versus chronic loss of mammalian Azi1/Cep131 results in distinct ciliary phenotypes.

Hall, Emma A; Keighren, Margaret; Ford, Matthew J; Davey, Tracey; Jarman, Andrew P; Smith, Lee B; Jackson, Ian J; Mill, Pleasantine

Hall, Emma A; Keighren, Margaret; Ford, Matthew J; Davey, Tracey; Jarman, Andrew P; Smith, Lee B; Jackson, Ian J; Mill, Pleasantine.

Afiliação

Hall EA; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine at The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.
Keighren M; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine at The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.
Ford MJ; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine at The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.
Davey T; Electron Microscopy Research Services, Medical School, Newcastle University, Newcastle, United Kingdom.
Jarman AP; Centre for Integrative Physiology, School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Smith LB; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom.
Jackson IJ; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine at The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.
Mill P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine at The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

PLoS Genet ; 9(12): e1003928, 2013.

Article em En | MEDLINE | ID: mdl-24415959

Assuntos

Cílios/genética; Infertilidade Masculina/genética; Proteínas/genética; Cauda do Espermatozoide/patologia; Animais; Proteínas de Ciclo Celular; Centríolos/genética; Centríolos/metabolismo; Cílios/patologia; Proteínas do Citoesqueleto; Flagelos/metabolismo; Flagelos/patologia; Regulação da Expressão Gênica no Desenvolvimento; Humanos; Infertilidade Masculina/etiologia; Masculino; Camundongos; Camundongos Knockout; Microtúbulos/metabolismo; Microtúbulos/patologia; Proteínas/metabolismo; RNA Interferente Pequeno

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cauda do Espermatozoide / Proteínas / Cílios / Infertilidade Masculina Tipo de estudo: Etiology_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Reino Unido

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