Differences in the pore sizes of the N-methyl-D-aspartate and kainate cation channels.
Neurosci Lett
; 89(3): 313-8, 1988 Jul 08.
Article
em En
| MEDLINE
| ID: mdl-2458553
ABSTRACT
The cation channels in central nervous system neurons gated by the glutamate agonists N-methyl-D-aspartate (NMDA) and kainate have been shown to be similar, but not identical. To analyze the differences in more detail, the permeabilities of the channels to cations of different sizes have been measured. The kainate channel appears to be larger, and the cation permeabilities are similar to those of the acetylcholine gated channel at the neuromuscular junction. The NMDA channel appears to be about 10% smaller in size.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Cátions
/
Ácido Aspártico
/
Canais Iônicos
/
Ácido Caínico
Limite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Ano de publicação:
1988
Tipo de documento:
Article