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A,D-seco-limonoids from the stems of Clausena emarginata.
Xia, Hong-Min; Li, Chuang-Jun; Yang, Jing-Zhi; Ma, Jie; Chen, Xiao-Guang; Zhang, Dan; Li, Li; Zhang, Dong-Ming.
Afiliação
  • Xia HM; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050, People's Republic of China.
J Nat Prod ; 77(4): 784-91, 2014 Apr 25.
Article em En | MEDLINE | ID: mdl-24593150
Twelve new A,D-seco-limonoids, clauemargines A-L (1-12), and three known analogues were isolated from the stems of Clausena emarginata. The absolute configurations of 1 and 5 were confirmed by X-ray crystallography and ECD spectroscopy, respectively. Compounds 1, 2, 8-10, and 13 showed moderate inhibitory effects on LPS-induced NO production (IC50 values<10 µM).
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Meliaceae / Limoninas / Clausena Limite: Animals / Humans Idioma: En Revista: J Nat Prod Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Meliaceae / Limoninas / Clausena Limite: Animals / Humans Idioma: En Revista: J Nat Prod Ano de publicação: 2014 Tipo de documento: Article