Infectious diseases, from HCV to cpe how susceptible are we?

ABSTRACT

Infectious diseases remain a leading cause of morbidity and mortality. Still, there is substantial variation in the individual outcome when humans are exposed to potentially pathogenic micro-organisms. At least, one of the factors involved in the individual susceptibility to infections, is the genetic diversity of the host's immune response. This article gives a concise overview of the actual knowledge on the genetic mechanisms underlying human susceptibility to infectious diseases and the methods that are used to investigate it.