Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans.

Bennett, Christopher F; Vander Wende, Helen; Simko, Marissa; Klum, Shannon; Barfield, Sarah; Choi, Haeri; Pineda, Victor V; Kaeberlein, Matt

Bennett, Christopher F; Vander Wende, Helen; Simko, Marissa; Klum, Shannon; Barfield, Sarah; Choi, Haeri; Pineda, Victor V; Kaeberlein, Matt.

Afiliação

Bennett CF; 1] Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA [2] Molecular and Cellular Biology Program, University of Washington, 1959 NE Pacific Street, Seattle, Washington 98195-7470, USA.
Vander Wende H; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.
Simko M; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.
Klum S; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.
Barfield S; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.
Choi H; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.
Pineda VV; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.
Kaeberlein M; Department of Pathology, University of Washington, 1959 NE Pacific Street, D-514, Box 357470, Seattle, Washington 98195-7470, USA.

Nat Commun ; 5: 3483, 2014 Mar 24.

Article em En | MEDLINE | ID: mdl-24662282

Assuntos

Caenorhabditis elegans/fisiologia; Longevidade/fisiologia; Mitocôndrias/metabolismo; Resposta a Proteínas não Dobradas/fisiologia; Animais; Caenorhabditis elegans/metabolismo; Proteínas de Caenorhabditis elegans/genética; Técnicas de Silenciamento de Genes; Proteínas de Fluorescência Verde; Interferência de RNA; Reação em Cadeia da Polimerase em Tempo Real; Fatores de Transcrição/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Resposta a Proteínas não Dobradas / Longevidade / Mitocôndrias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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