Immunohistological study of Crooke's cells.
Pathol Res Pract
; 183(5): 636-7, 1988 Sep.
Article
em En
| MEDLINE
| ID: mdl-2467271
ABSTRACT
By immunohistochemical methods, 28 postmortem pituitary glands with unequivocal Crooke's hyaline change were examined to identify the hyaline material. Crooke's hyaline was positive for 55-57 kilodalton (KD) cytokeratin (CK) but negative for 68 KD CK, vimentin, desmin, neurofilament and glial fibrillary acidic protein. Involucrin, a new marker for keratinocyte differentiation, could also not be demonstrated. It was concluded that Crooke's hyaline was an abnormally accumulated CK which is a normal constituent of the ACTH cell.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipófise
Limite:
Humans
Idioma:
En
Revista:
Pathol Res Pract
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
Japão