Localization of Fc gamma receptors and complement receptors CR1 on human peripheral nerve fibres by immunoelectron microscopy.
J Neuroimmunol
; 23(1): 29-33, 1989 Jun.
Article
em En
| MEDLINE
| ID: mdl-2470779
ABSTRACT
The localization of receptors for the Fc part of IgG (Fc gamma R) and for the complement C3b/C4b components (CR1) on human peripheral nerve fibres was investigated by indirect immunoperoxidase staining of frozen nerve sections with monoclonal antibodies. Transmission electron microscopy revealed that Fc gamma R and CR1 are localized to the entire surface membrane and inner membrane (axolemma) of the Schwann cell. Myelin and axons were not stained. The presence of Fc gamma R and CR1 in human Schwann cells adds further evidence for the immunocompetence of these cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nervos Periféricos
/
Imunoglobulina G
/
Complemento C3b
/
Receptores de Complemento
/
Receptores Fc
/
Antígenos de Diferenciação
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Neuroimmunol
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Noruega