Automated quantification of FISH signals in urinary cells enables the assessment of chromosomal aberration patterns characteristic for bladder cancer.

Köhler, Christina U; Martin, Laura; Bonberg, Nadine; Behrens, Thomas; Deix, Thomas; Braun, Katharina; Noldus, Joachim; Jöckel, Karl-Heinz; Erbel, Raimund; Sommerer, Florian; Tannapfel, Andrea; Harth, Volker; Käfferlein, Heiko U; Brüning, Thomas

Köhler, Christina U; Martin, Laura; Bonberg, Nadine; Behrens, Thomas; Deix, Thomas; Braun, Katharina; Noldus, Joachim; Jöckel, Karl-Heinz; Erbel, Raimund; Sommerer, Florian; Tannapfel, Andrea; Harth, Volker; Käfferlein, Heiko U; Brüning, Thomas.

Afiliação

Köhler CU; Institute of Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum, Bochum, Germany.
Martin L; Institute of Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum, Bochum, Germany.
Bonberg N; Institute of Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum, Bochum, Germany.
Behrens T; Institute of Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum, Bochum, Germany.
Deix T; Department of Urology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany.
Braun K; Department of Urology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany.
Noldus J; Department of Urology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany.
Jöckel KH; Institute of Medical Informatics, Biometry and Epidemiology, University Clinic Essen, Essen, Germany.
Erbel R; Clinic for Cardiology, West German Heart Center, University Clinic Essen, Essen, Germany.
Sommerer F; Institute of Pathology, Georgius Agricola Foundation Ruhr, Ruhr University Bochum, Bochum, Germany.
Tannapfel A; Institute of Pathology, Georgius Agricola Foundation Ruhr, Ruhr University Bochum, Bochum, Germany.
Harth V; Institute for Occupational and Maritime Medicine, University Clinic Hamburg-Eppendorf, Hamburg, Germany.
Käfferlein HU; Institute of Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum, Bochum, Germany. Electronic address: kaefferlein@ipa-dguv.de.
Brüning T; Institute of Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum, Bochum, Germany.

Biochem Biophys Res Commun ; 448(4): 467-72, 2014 Jun 13.

Article em En | MEDLINE | ID: mdl-24802410

Assuntos

Aberrações Cromossômicas; Hibridização in Situ Fluorescente/métodos; Neoplasias da Bexiga Urinária/diagnóstico; Neoplasias da Bexiga Urinária/genética; Idoso; Idoso de 80 Anos ou mais; Automação Laboratorial; Estudos de Casos e Controles; Centrômero/genética; Cromossomos Humanos Par 17/genética; Cromossomos Humanos Par 3/genética; Cromossomos Humanos Par 7/genética; Cromossomos Humanos Par 9/genética; Diagnóstico por Computador; Feminino; Humanos; Interpretação de Imagem Assistida por Computador; Hibridização in Situ Fluorescente/estatística & dados numéricos; Masculino; Pessoa de Meia-Idade; Projetos Piloto; Software; Neoplasias da Bexiga Urinária/urina; Urina/citologia

Palavras-chave

Automation; Bladder cancer; Fluorescence-in situ-hybridization; Image analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Aberrações Cromossômicas / Hibridização in Situ Fluorescente Tipo de estudo: Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha

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