High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody.

Babcock, Gregory J; Iyer, Sowmya; Smith, Heidi L; Wang, Yang; Rowley, Kirk; Ambrosino, Donna M; Zamore, Phillip D; Pierce, Brian G; Molrine, Deborah C; Weng, Zhiping

Babcock, Gregory J; Iyer, Sowmya; Smith, Heidi L; Wang, Yang; Rowley, Kirk; Ambrosino, Donna M; Zamore, Phillip D; Pierce, Brian G; Molrine, Deborah C; Weng, Zhiping.

Afiliação

Babcock GJ; MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, United States of America.
Iyer S; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America; Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America.
Smith HL; MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, United States of America.
Wang Y; MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, United States of America.
Rowley K; MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, United States of America.
Ambrosino DM; MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, United States of America.
Zamore PD; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Pierce BG; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Molrine DC; MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, United States of America.
Weng Z; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.

PLoS One ; 9(6): e100325, 2014.

Article em En | MEDLINE | ID: mdl-24956119

Assuntos

Anticorpos Monoclonais/farmacologia; Anticorpos Neutralizantes/farmacologia; Evolução Biológica; Biomarcadores/metabolismo; Hepatite C Crônica/terapia; Transplante de Fígado; Proteínas do Envelope Viral/imunologia; Sequência de Aminoácidos; Anticorpos Antivirais/imunologia; Método Duplo-Cego; Seguimentos; Glicosilação; Hepatite C Crônica/imunologia; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Dados de Sequência Molecular; Prognóstico; RNA Viral/sangue; RNA Viral/genética; Recidiva; Homologia de Sequência de Aminoácidos; Proteínas do Envelope Viral/antagonistas & inibidores

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Proteínas do Envelope Viral / Transplante de Fígado / Hepatite C Crônica / Evolução Biológica / Anticorpos Neutralizantes / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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