High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment.

Wu, Nicholas C; Young, Arthur P; Al-Mawsawi, Laith Q; Olson, C Anders; Feng, Jun; Qi, Hangfei; Luan, Harding H; Li, Xinmin; Wu, Ting-Ting; Sun, Ren

Wu, Nicholas C; Young, Arthur P; Al-Mawsawi, Laith Q; Olson, C Anders; Feng, Jun; Qi, Hangfei; Luan, Harding H; Li, Xinmin; Wu, Ting-Ting; Sun, Ren.

Afiliação

Wu NC; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA Molecular Biology Institute, University of California, Los Angeles, California, USA.
Young AP; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Al-Mawsawi LQ; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Olson CA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Feng J; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Qi H; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Luan HH; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Li X; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Wu TT; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Sun R; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA Molecular Biology Institute, University of California, Los Angeles, California, USA AIDS Institute, University of California, Los Angeles, California, USA RSun@me

J Virol ; 88(17): 10157-64, 2014 Sep 01.

Article em En | MEDLINE | ID: mdl-24965464

Assuntos

Vírus da Influenza A/imunologia; Vírus da Influenza A/fisiologia; Interferon Tipo I/antagonistas & inibidores; Mutação; Proteínas não Estruturais Virais/deficiência; Proteínas não Estruturais Virais/metabolismo; Sequenciamento de Nucleotídeos em Larga Escala; Vírus da Influenza A/genética; Vírus da Influenza A/crescimento & desenvolvimento; Biologia Molecular/métodos; RNA Viral/genética; Virologia/métodos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Interferon Tipo I / Proteínas não Estruturais Virais / Mutação Tipo de estudo: Diagnostic_studies Idioma: En Revista: J Virol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google