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A new mechanism of allostery in a G protein-coupled receptor dimer.
Lane, J Robert; Donthamsetti, Prashant; Shonberg, Jeremy; Draper-Joyce, Christopher J; Dentry, Samuel; Michino, Mayako; Shi, Lei; López, Laura; Scammells, Peter J; Capuano, Ben; Sexton, Patrick M; Javitch, Jonathan A; Christopoulos, Arthur.
Afiliação
  • Lane JR; Drug Discovery Biology, Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Donthamsetti P; 1] Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA. [2] Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York, USA. [3] Division of Molecular Therapeutics, New York State Psychiatric Institut
  • Shonberg J; Department of Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Draper-Joyce CJ; Drug Discovery Biology, Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Dentry S; Drug Discovery Biology, Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Michino M; United States Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, USA.
  • Shi L; 1] United States Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York, USA. [2] Institute for Computational Biomedicine, Weill Medical College of Cornell University, New York, New York, USA.
  • López L; Drug Discovery Biology, Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Scammells PJ; Department of Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Capuano B; Department of Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Sexton PM; Drug Discovery Biology, Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
  • Javitch JA; 1] Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA. [2] Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York, USA. [3] Division of Molecular Therapeutics, New York State Psychiatric Institut
  • Christopoulos A; Drug Discovery Biology, Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University-Parkville Campus, Parkville, Victoria, Australia.
Nat Chem Biol ; 10(9): 745-52, 2014 Sep.
Article em En | MEDLINE | ID: mdl-25108820
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dopaminérgicos / Receptores Acoplados a Proteínas G Limite: Animals / Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dopaminérgicos / Receptores Acoplados a Proteínas G Limite: Animals / Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália