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Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis.
Heselmeyer-Haddad, Kerstin M; Berroa Garcia, Lissa Y; Bradley, Amanda; Hernandez, Leanora; Hu, Yue; Habermann, Jens K; Dumke, Christoph; Thorns, Christoph; Perner, Sven; Pestova, Ekaterina; Burke, Catherine; Chowdhury, Salim A; Schwartz, Russell; Schäffer, Alejandro A; Paris, Pamela L; Ried, Thomas.
Afiliação
  • Heselmeyer-Haddad KM; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. Electronic address: heselmek@mail.nih.gov.
  • Berroa Garcia LY; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Bradley A; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Hernandez L; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Hu Y; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Habermann JK; Section for Translational Surgical Oncology and Biobanking, Department of Surgery, University of Lübeck and University Medical Center Schleswig-Holstein, Campus University of Lübeck, Lübeck, Germany.
  • Dumke C; Section for Translational Surgical Oncology and Biobanking, Department of Surgery, University of Lübeck and University Medical Center Schleswig-Holstein, Campus University of Lübeck, Lübeck, Germany.
  • Thorns C; Institute of Pathology, University of Lübeck and University Medical Center Schleswig-Holstein, Campus University of Lübeck, Lübeck, Germany.
  • Perner S; Department of Prostate Cancer Research, Institute of Pathology, University Hospital of Bonn, Bonn, Germany.
  • Pestova E; Abbott Molecular, Des Plaines, Illinois.
  • Burke C; Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
  • Chowdhury SA; Joint Carnegie Mellon/University of Pittsburgh Ph.D. Program in Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania; Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania.
  • Schwartz R; Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania.
  • Schäffer AA; Computational Biology Branch, National Center for Biotechnology Information, the National Institutes of Health, Bethesda, Maryland.
  • Paris PL; Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
  • Ried T; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Am J Pathol ; 184(10): 2671-86, 2014 Oct.
Article em En | MEDLINE | ID: mdl-25131421
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Adenocarcinoma / Biomarcadores Tumorais / PTEN Fosfo-Hidrolase Tipo de estudo: Prognostic_studies Limite: Aged / Humans / Male / Middle aged Idioma: En Revista: Am J Pathol Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Adenocarcinoma / Biomarcadores Tumorais / PTEN Fosfo-Hidrolase Tipo de estudo: Prognostic_studies Limite: Aged / Humans / Male / Middle aged Idioma: En Revista: Am J Pathol Ano de publicação: 2014 Tipo de documento: Article