Tear menisci and corneal subbasal nerve density in patients after laser in situ keratomileusis.
Eye Contact Lens
; 41(1): 51-7, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25230078
ABSTRACT
OBJECTIVE:
To investigate the relationship between tear menisci and corneal nerve density in patients after laser in situ keratomileusis (LASIK).METHODS:
Twenty-eight eyes of 14 myopic patients were enrolled. Height and area of the upper and lower tear menisci--upper tear meniscus height, upper tear meniscus area, lower tear meniscus height (LTMH), and lower tear meniscus area (LTMA)--were measured by spectral domain optical coherence tomography before surgery, 1 week, 1 month, and 3 months after surgery. Central, temporal, and nasal corneal nerve densities were measured by confocal microscopy before surgery, 1 month, and 3 months after surgery.RESULTS:
After surgery, LTMH and LTMA increased significantly from 1 week to 1 month (P=0.009 and =0.011, respectively) and 1 month to 3 months (P=0.003 and =0.039, respectively); temporal and nasal nerve densities increased significantly from 1 month to 3 months (P<0.001, P=0.016, respectively). Lower tear meniscus area was significantly correlated with central and nasal nerve densities at 1 month (R=0.478 and 0.46, P=0.01 and 0.014, respectively), whereas LTMH and LTMA at 3 months were significantly correlated with central nerve density at 1 month (R=0.449 and 0.608, P=0.017 and 0.001, respectively).CONCLUSIONS:
Lower tear menisci and peripheral corneal nerves recovered continually after LASIK during the early stage. However, tear volume might depend on residual central corneal nerves at 1 month, rather than on corneal nerve recovery.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lágrimas
/
Córnea
/
Ceratomileuse Assistida por Excimer Laser In Situ
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eye Contact Lens
Assunto da revista:
OFTALMOLOGIA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
China