Association of G197 polymorphism of IL-17A gene with myocardial remodeling and aerobic performance in athletes.

ABSTRACT

We studied the relationship between G197A polymorphism of IL-17A gene and changes in morphometric echocardiography parameters and physiological parameters in skiers (19 examinees). Genotyping was performed by restriction fragment length polymorphism analysis and echocardiography using a Nemio MX ultrasound scanner (Toshiba). Association of 197A allele of IL-17A gene with low myocardial growth and high aerobic performance of athletes was demonstrated.