Radioiodinated fatty acid esters in the management of hepatocellular carcinoma: preliminary findings.
Cancer Chemother Pharmacol
; 23 Suppl: S54-8, 1989.
Article
em En
| MEDLINE
| ID: mdl-2538267
ABSTRACT
Radioiodinated fatty acid esters, such as lipiodol or ethiodol, are localized in the hypervascular hepatocellular carcinoma (HCC) for a long time following intra-arterial hepatic injection, enabling delivery of high internal radiation to the tumor. The desired radiation can easily be delivered to small HCC, less than 5 cm in diameter, in single or multiple procedures with an 8-week interval. For larger tumors, [131I]lipiodol or [131I]ethiodol in conjunction with chemotherapy emulsion, Ivalon embolization or all three combinations should be considered for maximal clinical results. A strong beta emitter with shorter physical half-life, i.e. 90Y will be more effective in the management of HCC if one can label lipiodol with 90Y.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Óleo Iodado
/
Carcinoma Hepatocelular
/
Embolização Terapêutica
/
Radioisótopos do Iodo
/
Neoplasias Hepáticas
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cancer Chemother Pharmacol
Ano de publicação:
1989
Tipo de documento:
Article