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Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice.
Hagiya, Yoshifumi; Kamata, Shotaro; Mitsuoka, Saya; Okada, Norihiko; Yoshida, Saori; Yamamoto, Junya; Ohkubo, Rika; Abiko, Yumi; Yamada, Hidenori; Akahoshi, Noriyuki; Kasahara, Tadashi; Kumagai, Yoshito; Ishii, Isao.
Afiliação
  • Hagiya Y; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Kamata S; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Mitsuoka S; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Okada N; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Yoshida S; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Yamamoto J; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Ohkubo R; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Abiko Y; Environmental Biology Laboratory, School of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.
  • Yamada H; Jobu Hospital for Respiratory Diseases, Maebashi 371-0048, Japan.
  • Akahoshi N; Department of Immunology, Akita University Graduate School of Medicine, Akita 010-8543, Japan.
  • Kasahara T; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan.
  • Kumagai Y; Environmental Biology Laboratory, School of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.
  • Ishii I; Department of Biochemistry, Keio University School of Pharmaceutical Sciences, Tokyo 105-8512, Japan. Electronic address: isao-ishii@umin.ac.jp.
Toxicol Appl Pharmacol ; 282(2): 195-206, 2015 Jan 15.
Article em En | MEDLINE | ID: mdl-25499718
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfatos / Zigoto / Analgésicos não Narcóticos / Doença Hepática Induzida por Substâncias e Drogas / Acetaminofen Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfatos / Zigoto / Analgésicos não Narcóticos / Doença Hepática Induzida por Substâncias e Drogas / Acetaminofen Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão