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HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.
O'Connell, Brenda C; O'Callaghan, Katie; Tillotson, Bonnie; Douglas, Mark; Hafeez, Nafeeza; West, Kip A; Stern, Howard; Ali, Janid A; Changelian, Paul; Fritz, Christian C; Palombella, Vito J; McGovern, Karen; Kutok, Jeffery L.
Afiliação
  • O'Connell BC; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • O'Callaghan K; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Tillotson B; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Douglas M; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Hafeez N; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • West KA; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Stern H; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Ali JA; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Changelian P; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Fritz CC; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Palombella VJ; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • McGovern K; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
  • Kutok JL; Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.
PLoS One ; 9(12): e115228, 2014.
Article em En | MEDLINE | ID: mdl-25542032
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzoquinonas / Carcinoma Pulmonar de Células não Pequenas / Proteínas de Choque Térmico HSP90 / Taxoides / Lactamas Macrocíclicas / Neoplasias Pulmonares Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzoquinonas / Carcinoma Pulmonar de Células não Pequenas / Proteínas de Choque Térmico HSP90 / Taxoides / Lactamas Macrocíclicas / Neoplasias Pulmonares Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos