Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.

Chong, Yong Chun; Mann, Randall K; Zhao, Chen; Kato, Masaki; Beachy, Philip A

Chong, Yong Chun; Mann, Randall K; Zhao, Chen; Kato, Masaki; Beachy, Philip A.

Afiliação

Chong YC; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA; Department of Developmental Biology, Stanford University, Stanford, California 94305, USA; Department of Biochemistry, Stanford University, Stanford, California 94305, USA;
Mann RK; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA; Department of Developmental Biology, Stanford University, Stanford, California 94305, USA; Department of Biochemistry, Stanford University, Stanford, California 94305, USA;
Zhao C; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA; Department of Developmental Biology, Stanford University, Stanford, California 94305, USA; Department of Biochemistry, Stanford University, Stanford, California 94305, USA;
Kato M; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA; Department of Developmental Biology, Stanford University, Stanford, California 94305, USA;
Beachy PA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA; Department of Developmental Biology, Stanford University, Stanford, California 94305, USA; Department of Biochemistry, Stanford University, Stanford, California 94305, USA; Howard Hughes

Genes Dev ; 29(3): 262-76, 2015 Feb 01.

Article em En | MEDLINE | ID: mdl-25644602

Assuntos

Guanilato Quinases/metabolismo; Proteínas Hedgehog/metabolismo; Proteínas de Membrana/metabolismo; Receptores Acoplados a Proteínas G/metabolismo; Transdução de Sinais; Motivos de Aminoácidos; Animais; Corpos Basais/metabolismo; Linhagem Celular; Cílios/metabolismo; Guanilato Quinases/genética; Células HEK293; Humanos; Cinesinas/metabolismo; Fatores de Transcrição Kruppel-Like/metabolismo; Proteínas de Membrana/genética; Camundongos; Células NIH 3T3; Proteínas do Tecido Nervoso/metabolismo; Ligação Proteica; Transporte Proteico; Receptores Acoplados a Proteínas G/genética; Receptor Smoothened; Proteína Gli2 com Dedos de Zinco; Proteína Gli3 com Dedos de Zinco

Palavras-chave

Dlg5; Gli; Hedgehog; Kif7; Smoothened; basal body

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores Acoplados a Proteínas G / Guanilato Quinases / Proteínas Hedgehog / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article

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