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Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7.
Staropoli, John F; Li, Huo; Chun, Seung J; Allaire, Norm; Cullen, Patrick; Thai, Alice; Fleet, Christina M; Hua, Yimin; Bennett, C Frank; Krainer, Adrian R; Kerr, Doug; McCampbell, Alexander; Rigo, Frank; Carulli, John P.
Afiliação
  • Staropoli JF; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • Li H; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • Chun SJ; Neuroscience Drug Discovery, Isis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Allaire N; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • Cullen P; Neuroscience Drug Discovery, Isis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Thai A; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • Fleet CM; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • Hua Y; Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
  • Bennett CF; Neuroscience Drug Discovery, Isis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Krainer AR; Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
  • Kerr D; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • McCampbell A; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA.
  • Rigo F; Neuroscience Drug Discovery, Isis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Carulli JP; Division of Genetics and Genomics, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA. Electronic address: john.carulli@biogenidec.com.
Genomics ; 105(4): 220-8, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25645699
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atrofia Muscular Espinal / Expressão Gênica / Éxons / Oligonucleotídeos Antissenso Limite: Animals Idioma: En Revista: Genomics Assunto da revista: GENETICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atrofia Muscular Espinal / Expressão Gênica / Éxons / Oligonucleotídeos Antissenso Limite: Animals Idioma: En Revista: Genomics Assunto da revista: GENETICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos