Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate.

Fortier, Simon; MacRae, Tara; Bilodeau, Mélanie; Sargeant, Tobias; Sauvageau, Guy

Fortier, Simon; MacRae, Tara; Bilodeau, Mélanie; Sargeant, Tobias; Sauvageau, Guy.

Afiliação

Fortier S; Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3C 3J7, Canada;
MacRae T; Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3C 3J7, Canada;
Bilodeau M; Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3C 3J7, Canada;
Sargeant T; Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3C 3J7, Canada; Division of Molecular Medicine, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3050, Australia; and Department of Medical Biol
Sauvageau G; Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3C 3J7, Canada; guy.sauvageau@umontreal.ca.

Proc Natl Acad Sci U S A ; 112(7): 2127-32, 2015 Feb 17.

Article em En | MEDLINE | ID: mdl-25646475

Assuntos

Linhagem da Célula; Células-Tronco Embrionárias/citologia; Haploinsuficiência; Proteínas Ribossômicas/genética; Animais; Linhagem Celular; Humanos; Masculino; Camundongos; Proteína Supressora de Tumor p53/genética

Palavras-chave

differentiation; embryoid body; embryonic stem cells; ribosomal proteins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Ribossômicas / Linhagem da Célula / Células-Tronco Embrionárias / Haploinsuficiência Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article

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