Caveolin-1, galectin-3 and lipid raft domains in cancer cell signalling.
Essays Biochem
; 57: 189-201, 2015.
Article
em En
| MEDLINE
| ID: mdl-25658354
ABSTRACT
Spatial organization of the plasma membrane is an essential feature of the cellular response to external stimuli. Receptor organization at the cell surface mediates transmission of extracellular stimuli to intracellular signalling molecules and effectors that impact various cellular processes including cell differentiation, metabolism, growth, migration and apoptosis. Membrane domains include morphologically distinct plasma membrane invaginations such as clathrin-coated pits and caveolae, but also less well-defined domains such as lipid rafts and the galectin lattice. In the present chapter, we will discuss interaction between caveolae, lipid rafts and the galectin lattice in the control of cancer cell signalling.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
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Regulação Neoplásica da Expressão Gênica
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Microdomínios da Membrana
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Galectina 3
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Caveolina 1
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Receptores ErbB
Limite:
Humans
Idioma:
En
Revista:
Essays Biochem
Ano de publicação:
2015
Tipo de documento:
Article