Gamma-hydroxybutyric acid for treatment of alcohol withdrawal syndrome.
Lancet
; 2(8666): 787-9, 1989 Sep 30.
Article
em En
| MEDLINE
| ID: mdl-2571021
ABSTRACT
The effect of gamma-hydroxybutyric acid (GHB) on ethanol withdrawal syndrome in alcoholics was investigated in a randomised double-blind study. Patients with withdrawal symptoms were treated either with GHB (orally in a syrup preparation) (11 patients) or with the syrup alone (12). GHB treatment (50 mg/kg) led to a prompt reduction in withdrawal symptoms, such as tremors, sweating, nausea, depression, anxiety, and restlessness. The only side-effect was dizziness. GHB may be useful in the management of alcohol withdrawal syndrome in man.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxibato de Sódio
/
Síndrome de Abstinência a Substâncias
/
Etanol
/
Hidroxibutiratos
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Lancet
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Itália