Protein kinase A (PknA) of Mycobacterium tuberculosis is independently activated and is critical for growth in vitro and survival of the pathogen in the host.

Nagarajan, Sathya Narayanan; Upadhyay, Sandeep; Chawla, Yogesh; Khan, Shazia; Naz, Saba; Subramanian, Jayashree; Gandotra, Sheetal; Nandicoori, Vinay Kumar

Nagarajan, Sathya Narayanan; Upadhyay, Sandeep; Chawla, Yogesh; Khan, Shazia; Naz, Saba; Subramanian, Jayashree; Gandotra, Sheetal; Nandicoori, Vinay Kumar.

Afiliação

Nagarajan SN; From the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India, the Department of Biotechnology, Nehru Arts and Science College, Coimbatore 641105, India, and.
Upadhyay S; From the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Chawla Y; From the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Khan S; From the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Naz S; From the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Subramanian J; the Department of Biotechnology, Nehru Arts and Science College, Coimbatore 641105, India, and.
Gandotra S; CSIR-Institute of Genomics and Integrative Biology, Mathura Road, New Delhi 110020, India.
Nandicoori VK; From the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India, vinaykn@nii.ac.in.

J Biol Chem ; 290(15): 9626-45, 2015 Apr 10.

Article em En | MEDLINE | ID: mdl-25713147

Assuntos

Proteínas de Bactérias/metabolismo; Viabilidade Microbiana; Mycobacterium tuberculosis/enzimologia; Proteínas Serina-Treonina Quinases/metabolismo; Animais; Proteínas de Bactérias/genética; Biocatálise; Western Blotting; Ativação Enzimática; Feminino; Interações Hospedeiro-Patógeno; Masculino; Camundongos Endogâmicos C57BL; Microscopia Eletrônica de Varredura; Microscopia de Fluorescência; Mutação; Mycobacterium tuberculosis/genética; Mycobacterium tuberculosis/fisiologia; Fosforilação; Proteínas Serina-Treonina Quinases/genética; Tuberculose/microbiologia

Palavras-chave

Bacterial Protein Kinase; Cell Signaling; Conditional Mutant; Mutant; Mycobacterium tuberculosis; Phosphorylation; PknA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Proteínas Serina-Treonina Quinases / Viabilidade Microbiana / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article

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