Development of an in vivo glucosylation platform by coupling production to growth: Production of phenolic glucosides by a glycosyltransferase of Vitis vinifera.

De Bruyn, Frederik; De Paepe, Brecht; Maertens, Jo; Beauprez, Joeri; De Cocker, Pieter; Mincke, Stein; Stevens, Christian; De Mey, Marjan

De Bruyn, Frederik; De Paepe, Brecht; Maertens, Jo; Beauprez, Joeri; De Cocker, Pieter; Mincke, Stein; Stevens, Christian; De Mey, Marjan.

Afiliação

De Bruyn F; Centre of Expertise - Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, 9000, Ghent, Belgium. Frederik.DeBruyn@Ugent.be.
De Paepe B; Centre of Expertise - Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, 9000, Ghent, Belgium.
Maertens J; Centre of Expertise - Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, 9000, Ghent, Belgium.
Beauprez J; Centre of Expertise - Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, 9000, Ghent, Belgium.
De Cocker P; Centre of Expertise - Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, 9000, Ghent, Belgium.
Mincke S; Research Group SynBioC, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, 9000, Ghent, Belgium.
Stevens C; Research Group SynBioC, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, 9000, Ghent, Belgium.
De Mey M; Centre of Expertise - Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, 9000, Ghent, Belgium.

Biotechnol Bioeng ; 112(8): 1594-603, 2015 Aug.

Article em En | MEDLINE | ID: mdl-25728421

Assuntos

Escherichia coli/metabolismo; Glucosídeos/metabolismo; Glicosiltransferases/metabolismo; Engenharia Metabólica/métodos; Fenóis/metabolismo; Vitis/enzimologia; Metabolismo Energético; Escherichia coli/genética; Frutose/metabolismo; Deleção de Genes; Glucofosfatos/metabolismo; Glucosiltransferases/genética; Glucosiltransferases/metabolismo; Glicosiltransferases/genética; Organismos Geneticamente Modificados/genética; Organismos Geneticamente Modificados/metabolismo; Uridina Difosfato Glucose/metabolismo; Vitis/genética

Palavras-chave

Escherichia coli W; UDP-glucose; glucogallin; glucosylation; metabolic engineering; phenolic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Glicosiltransferases / Vitis / Escherichia coli / Engenharia Metabólica / Glucosídeos Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Bélgica

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