Antibacterial Polyketide Heterodimers from Pyrenacantha kaurabassana Tubers.
J Nat Prod
; 78(4): 597-603, 2015 Apr 24.
Article
em En
| MEDLINE
| ID: mdl-25756503
ABSTRACT
Two heterodimers comprising anthraquinone and methylbenzoisocoumarin moieties (1 and 2) were isolated, together with emodin and physcion from the tubers of Pyrenacantha kaurabassana. The structures of 1 and 2 were established by NMR spectroscopy, including the analysis of a 2D INADEQUATE spectrum. On the basis of the data obtained, the structures that were previously proposed in the literature for these compounds were revised. Compounds 1 and 2 showed antibacterial activity against three different strains of Staphylococcus aureus. Compound 2 also showed bactericidal activity against Helicobacter pylori.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antraquinonas
/
Magnoliopsida
/
Cumarínicos
/
Policetídeos
/
Antibacterianos
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
França